| Gene Information | |
|---|---|
| Gene Name | DMRTA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 504 |
| Protein Names | Doublesex- and mab-3-related transcription factor A1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000176399 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5VZB9 |
| Gene Card | DMRTA1 |
| Uniprot ID | Q5VZB9 |
| Pfam | PF00751; PF03474; PF20624 |
| In ASD | no |
| Allosteric Prediction | no (-0.987108943) |
| Ortholog in Animals | Alpaca_ DMRTA1 ( ortholog_one2one ) Dog_ DMRTA1 ( ortholog_one2one ) GuineaPig_ DMRTA1 ( ortholog_one2one ) Macaque_ DMRTA1 ( ortholog_one2one ) Mouse_ Dmrta1 ( ortholog_one2one ) Pig_ DMRTA1 ( ortholog_one2one ) Rat_ Dmrta1 ( ortholog_one2one ) Rabbit_ DMRTA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DMRTB1, DMRT1, DMRT3, DMRT2, DMRTC2, DMRTA2, DMRTC1, DMRTC1B |
| Tissue | NA |
| Tissue Specificity | Expressed in liver, kidney, pancreas, prostate and weakly detected in testis and ovary. {ECO:0000269|PubMed:11863363}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs372873186 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}. |
| Mouse PG classification | NA |
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