| Gene Information | |
|---|---|
| Gene Name | GATA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 443 |
| Protein Names | Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000107485 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P23771 |
| Gene Card | GATA3 |
| Uniprot ID | P23771 |
| Pfam | PF00320 |
| In ASD | no |
| Allosteric Prediction | yes (0.516112267) |
| Ortholog in Animals | Alpaca_ GATA3 ( ortholog_one2one ) Dog_ GATA3 ( ortholog_one2one ) GuineaPig_ GATA3 ( ortholog_one2one ) Macaque_ GATA3 ( ortholog_one2one ) Mouse_ Gata3 ( ortholog_one2one ) Pig_ GATA3 ( ortholog_one2one ) Rat_ Gata3 ( ortholog_one2one ) Rabbit_ GATA3 ( ortholog_one2one ) |
| Ohnologs | GATA2 |
| Paralogs | ZGLP1, GATA2, GATA5, GATA6, TRPS1, GATA1, GATA4 |
| Tissue | breast, placenta, seminal.vesicle, vas.deferens, zone.of.skin, kidney, spleen, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | T-cells and endothelial cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4HC7 (X-ray 2.65A ) 4HC9 (X-ray 1.60A ) 4HCA (X-ray 2.80A ) |
| DBSNP | rs11567901 rs104894163 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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