| Gene Information | |
|---|---|
| Gene Name | ANO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1003 |
| Protein Names | Anoctamin-2 (Transmembrane protein 16B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000047617 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NQ90 |
| Gene Card | ANO2 |
| Uniprot ID | Q9NQ90 |
| Pfam | PF16178; PF04547 |
| In ASD | no |
| Allosteric Prediction | no (-0.683097997) |
| Ortholog in Animals | Alpaca_ ANO2 ( ortholog_one2one ) Dog_ ANO2 ( ortholog_one2one ) GuineaPig_ ANO2 ( ortholog_one2one ) Mouse_ Ano2 ( ortholog_one2one ) Rat_ Ano2 ( ortholog_one2one ) |
| Ohnologs | ANO6, ANO1, ANO3, ANO7, ANO5 |
| Paralogs | ANO8, ANO4, PPP1R7, ANO7, ANO5, ANO6, ANO1, ANO10, ANO9, ANO3 |
| Tissue | testis |
| Tissue Specificity | Retina, especially in the photoreceptor synaptic terminals. {ECO:0000269|PubMed:19474308}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3741903 rs3741901 rs17788563 rs1860961 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:20056604}; Multi-pass membrane protein {ECO:0000269|PubMed:20056604}. |
| Mouse PG classification | NA |
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