Gene Information
Gene NameNIBAN2
OrganismHomo sapiens (Human)
Gene Length746
Protein NamesProtein Niban 2 (Meg-3) (Melanoma invasion by ERK) (MINERVA) (Niban-like protein 1) (Protein FAM129B)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000136830 )
Evolutionary StageEukaryota
AlphaFoldDBQ96TA1
Gene CardNIBAN2
Uniprot IDQ96TA1
PfamNA
In ASDno
Allosteric Predictionno (-1.336921976)
Ortholog in AnimalsAlpaca_ NIBAN2 ( ortholog_one2one )
Dog_ NIBAN2 ( ortholog_one2one )
GuineaPig_ NIBAN2 ( ortholog_one2one )
Macaque_ NIBAN2 ( ortholog_one2one )
Mouse_ Niban2 ( ortholog_one2one )
Pig_ NIBAN2 ( ortholog_one2one )
Rat_ Niban2 ( ortholog_one2one )
Rabbit_ NIBAN2 ( ortholog_one2one )
OhnologsNA
ParalogsNIBAN3, NIBAN1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7CTP  (X-ray  1.80A 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytosol. Cell junction, adherens junction. Membrane {ECO:0000305};
Lipid-anchor {ECO:0000305}. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation.
Mouse PG classificationNA
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