| Gene Information | |
|---|---|
| Gene Name | DLL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 618 |
| Protein Names | Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3) |
| Target Name | delta-like protein 3 |
| Target Type | Clinical trial target |
| Gene Age | 1064 ( ENSG00000090932 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9NYJ7 |
| Gene Card | DLL3 |
| Uniprot ID | Q9NYJ7 |
| Pfam | PF00008; PF12661; PF07657 |
| In ASD | no |
| Allosteric Prediction | no (-1.50137611) |
| Ortholog in Animals | Alpaca_ DLL3 ( ortholog_one2many ) Dog_ DLL3 ( ortholog_one2one ) GuineaPig_ DLL3 ( ortholog_one2one ) Macaque_ DLL3 ( ortholog_one2one ) Mouse_ Dll3 ( ortholog_one2one ) Pig_ DLL3 ( ortholog_one2one ) Rat_ Dll3 ( ortholog_one2one ) Rabbit_ DLL3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRELD2, FBLN7, WIF1, DLK2, CD93, CD248, CRELD1, CLEC14A |
| Tissue | brain |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs71647811 rs55741253 rs8107127 rs1110627 rs104894674 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | HPG |
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