| Gene Information | |
|---|---|
| Gene Name | CRTAC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 661 |
| Protein Names | Cartilage acidic protein 1 (68 kDa chondrocyte-expressed protein) (CEP-68) (ASPIC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000095713 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NQ79 |
| Gene Card | CRTAC1 |
| Uniprot ID | Q9NQ79 |
| Pfam | PF07645; PF13517; PF07593 |
| In ASD | no |
| Allosteric Prediction | no (-1.537384235) |
| Ortholog in Animals | Alpaca_ CRTAC1 ( ortholog_one2one ) Dog_ CRTAC1 ( ortholog_one2one ) GuineaPig_ CRTAC1 ( ortholog_one2one ) Macaque_ CRTAC1 ( ortholog_one2one ) Mouse_ Crtac1 ( ortholog_one2one ) Pig_ CRTAC1 ( ortholog_one2one ) Rat_ Crtac1 ( ortholog_one2one ) Rabbit_ CRTAC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | lung, oviduct |
| Tissue Specificity | Expressed in the interterritorial matrix of articular deep zone cartilage (at protein level). Isoform 1 and isoform 2 are expressed in brain. Isoform 1 is detected in lung and chondrocytes. Detected in cartilage, bone, cultured chondrocytes and lung, and at low levels in heart. Not detected in osteoblasts. {ECO:0000269|PubMed:11139377, ECO:0000269|PubMed:17074475}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35853031 rs2297935 rs56007204 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17074475}. |
| Mouse PG classification | NA |
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