| Gene Information | |
|---|---|
| Gene Name | DLGAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 977 |
| Protein Names | Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000170579 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14490 |
| Gene Card | DLGAP1 |
| Uniprot ID | O14490 |
| Pfam | PF03359 |
| In ASD | no |
| Allosteric Prediction | yes (0.129883716) |
| Ortholog in Animals | Alpaca_ DLGAP1 ( ortholog_one2one ) Dog_ DLGAP1 ( ortholog_one2one ) GuineaPig_ DLGAP1 ( ortholog_one2one ) Macaque_ DLGAP1 ( ortholog_one2one ) Mouse_ Dlgap1 ( ortholog_one2one ) Pig_ DLGAP1 ( ortholog_one2one ) Rat_ Dlgap1 ( ortholog_one2one ) Rabbit_ DLGAP1 ( ortholog_one2one ) |
| Ohnologs | DLGAP4, DLGAP3, DLGAP2 |
| Paralogs | DLGAP4, DLGAP3, DLGAP2, DLGAP5 |
| Tissue | brain, cerebral.cortex, amygdala, cerebellar.hemisphere, cerebellum, hippocampus |
| Tissue Specificity | Expressed in brain. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.02963(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5YPO (X-ray 2.29A ) 6TNQ (X-ray 1.30A ) 6TQ0 (X-ray 1.95A ) |
| DBSNP | rs35822832 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Postsynaptic density {ECO:0000250}. Synapse {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |