| Gene Information | |
|---|---|
| Gene Name | DLG6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 637 |
| Protein Names | MAGUK p55 subfamily member 4 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein) (Discs large homolog 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96JB8 |
| Gene Card | MPP4 |
| Uniprot ID | Q96JB8 |
| Pfam | PF00625; PF02828; PF00595 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the retina (at protein level). Highly expressed in the retina. Lower amounts are detected in brain, testis, ARPE-19, RPE/choroid and fetal eye. Isoform 5 is retina-specific. {ECO:0000269|PubMed:11414766, ECO:0000269|PubMed:12384283, ECO:0000269|PubMed:15558731, ECO:0000269|PubMed:15914641}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6725443 rs11894115 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15914641}. Note=Detected at the outer limiting membrane (OLM) and in the outer plexiform layer (OPL) of the retina. At the OLM, detected apical to the adherens junction (AJ). |
| Mouse PG classification | NA |
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