| Gene Information | |
|---|---|
| Gene Name | KIR2DL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 341 |
| Protein Names | Killer cell immunoglobulin-like receptor 2DL3 (CD158 antigen-like family member B2) (KIR-023GB) (Killer inhibitory receptor cl 2-3) (NKAT2a) (NKAT2b) (Natural killer-associated transcript 2) (NKAT-2) (p58 natural killer cell receptor clone CL-6) (p58 NK receptor CL-6) (p58.2 MHC class-I-specific NK receptor) (CD antigen CD158b2) |
| Target Name | mhc class i nk cell receptor 2dl3 |
| Target Type | Clinical trial target |
| Gene Age | 86 ( ENSG00000243772 ) 3 ( ENSG00000273887 ) 3 ( ENSG00000273947 ) 3 ( ENSG00000274108 ) 3 ( ENSG00000274402 ) 3 ( ENSG00000274410 ) 3 ( ENSG00000274830 ) 3 ( ENSG00000274952 ) 3 ( ENSG00000275008 ) 3 ( ENSG00000275623 ) 3 ( ENSG00000275658 ) 3 ( ENSG00000276218 ) 3 ( ENSG00000276459 ) 3 ( ENSG00000276590 ) 3 ( ENSG00000277317 ) 3 ( ENSG00000277484 ) 3 ( ENSG00000277554 ) 3 ( ENSG00000277924 ) 3 ( ENSG00000278327 ) 3 ( ENSG00000278369 ) 3 ( ENSG00000283702 ) 3 ( ENSG00000283708 ) 3 ( ENSG00000283790 ) 3 ( ENSG00000283996 ) 3 ( ENSG00000284044 ) 3 ( ENSG00000284132 ) 3 ( ENSG00000284236 ) 3 ( ENSG00000284241 ) 3 ( ENSG00000284333 ) 3 ( ENSG00000284504 ) 3 ( ENSG00000284510 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P43628 |
| Gene Card | KIR2DL3 |
| Uniprot ID | P43628 |
| Pfam | PF00047 |
| In ASD | no |
| Allosteric Prediction | no (-0.943348572) |
| Ortholog in Animals | Alpaca_ KIR2DL1 ( ortholog_one2many ) Alpaca_ KIR3DL5 ( ortholog_one2many ) Alpaca_ KIR2DL3 ( ortholog_one2many ) Mouse_ Kir3dl1 ( ortholog_many2many ) Mouse_ Kir3dl2 ( ortholog_many2many ) Rat_ Kir3dl1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | KIR2DL1, KIR2DS4, KIR3DL3, KIR3DL2, KIR3DL1, KIR2DL4, FCAR, LILRB2, LILRB5, LILRA2, LILRA4, LILRA6, LILRA5, NCR1, LILRB4, LILRB1, LILRA1, LILRB3, GP6, IGSF1, OSCAR, TARM1, VSTM1, LAIR2, A1BG |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1B6U (X-ray 3.00A ) 6PAG (X-ray 2.50A ) |
| DBSNP | rs3810343 rs202032116 rs683003 rs613240 rs35719984 rs78713511 rs138897134 rs35861855 rs4020187 rs1049267 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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