Gene Information
Gene NameDLEC1
OrganismHomo sapiens (Human)
Gene Length1755
Protein NamesDeleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000008226 )
Evolutionary StageEukaryota
AlphaFoldDBQ9Y238
Gene CardDLEC1
Uniprot IDQ9Y238
PfamNA
In ASDno
Allosteric Predictionno (-1.124788786)
Ortholog in AnimalsAlpaca_ DLEC1 ( ortholog_one2one )
Dog_ DLEC1 ( ortholog_one2one )
GuineaPig_ DLEC1 ( ortholog_one2one )
Macaque_ DLEC1 ( ortholog_one2one )
Mouse_ Dlec1 ( ortholog_one2one )
Pig_ DLEC1 ( ortholog_one2one )
Rat_ Dlec1 ( ortholog_one2one )
OhnologsNA
ParalogsCFAP47, HYDIN
Tissuetestis, oviduct, caudate.nucleus, epididymis, lung, medulla.oblongata, pituitary.gland
Tissue SpecificityExpressed in all tissues examined. Expression is highest in prostate and testis. {ECO:0000269|PubMed:10213508}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs7625806  rs34012183  rs36012922  rs9840172  rs9810085 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:10213508, ECO:0000269|PubMed:33144677}.
Mouse PG classificationNA
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