Gene Information
Gene NameDKK4
OrganismHomo sapiens (Human)
Gene Length224
Protein NamesDickkopf-related protein 4 (Dickkopf-4) (Dkk-4) (hDkk-4) [Cleaved into: Dickkopf-related protein 4 short form]
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000104371 )
Evolutionary StageMammalia
AlphaFoldDBQ9UBT3
Gene CardDKK4
Uniprot IDQ9UBT3
PfamPF04706; PF06607
In ASDno
Allosteric Predictionno (-1.188298976)
Ortholog in AnimalsAlpaca_ DKK4 ( ortholog_one2one )
Dog_ DKK4 ( ortholog_one2one )
GuineaPig_ DKK4 ( ortholog_one2one )
Macaque_ DKK4 ( ortholog_one2one )
Mouse_ Dkk4 ( ortholog_one2one )
Pig_ DKK4 ( ortholog_one2one )
Rat_ Dkk4 ( ortholog_one2one )
OhnologsDKK1, DKK2
ParalogsNA
TissueNA
Tissue SpecificityExpressed in cerebellum, T-cells, esophagus and lung.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5O57  (NMR 
DBSNP NA 
Subcellular location [CC]Secreted.
Mouse PG classificationNA
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