| Gene Information | |
|---|---|
| Gene Name | DKK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 350 |
| Protein Names | Dickkopf-related protein 3 (Dickkopf-3) (Dkk-3) (hDkk-3) |
| Target Name | dickkopf-related protein 3 |
| Target Type | Clinical trial target |
| Gene Age | 1064 ( ENSG00000050165 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UBP4 |
| Gene Card | DKK3 |
| Uniprot ID | Q9UBP4 |
| Pfam | PF04706 |
| In ASD | no |
| Allosteric Prediction | no (-0.220103206) |
| Ortholog in Animals | Alpaca_ DKK3 ( ortholog_one2one ) Dog_ DKK3 ( ortholog_one2one ) GuineaPig_ DKK3 ( ortholog_one2one ) Macaque_ DKK3 ( ortholog_one2one ) Mouse_ Dkk3 ( ortholog_one2one ) Pig_ DKK3 ( ortholog_one2one ) Rat_ Dkk3 ( ortholog_one2one ) Rabbit_ DKK3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest expression in heart, brain, and spinal cord. {ECO:0000269|PubMed:10570958, ECO:0000269|Ref.4}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11544816 rs3206824 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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