| Gene Information | |
|---|---|
| Gene Name | DIS3L2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 885 |
| Protein Names | DIS3-like exonuclease 2 (hDIS3L2) (EC 3.1.13.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000144535 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8IYB7 |
| Gene Card | DIS3L2 |
| Uniprot ID | Q8IYB7 |
| Pfam | PF17877; PF17849; PF00773; PF17216 |
| In ASD | no |
| Allosteric Prediction | no (-1.02128559) |
| Ortholog in Animals | Alpaca_ DIS3L2 ( ortholog_one2one ) Dog_ DIS3L2 ( ortholog_one2one ) GuineaPig_ DIS3L2 ( ortholog_one2one ) Macaque_ DIS3L2 ( ortholog_one2one ) Mouse_ Dis3l2 ( ortholog_one2one ) Pig_ DIS3L2 ( ortholog_one2one ) Rat_ Dis3l2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DIS3L, DIS3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.019048(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs723044 rs186865544 rs387907116 rs200386096 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:24141620}. Cytoplasm, P-body. |
| Mouse PG classification | NA |
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