Gene Information
Gene NameDIAP3
OrganismHomo sapiens (Human)
Gene Length1193
Protein NamesProtein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (MDia2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9NSV4
Gene CardDIAPH3
Uniprot IDQ9NSV4
PfamPF06367; PF06371; PF02181
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.036364(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5UWP  (X-ray  2.05A  6X2Y  (X-ray  2.30A 
DBSNP rs36084898  rs35579086  rs7491389 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:18755006, ECO:0000269|PubMed:19457867}. Nucleus {ECO:0000250|UniProtKB:Q9Z207}. Note=During mitosis, co-localizes with the actin-rich cleavage furrow and with the microtubule-rich central spindle during cytokinesis (PubMed:18755006, PubMed:19457867). Shuttles between the cytoplasm and the nucleus (By similarity). {ECO:0000250|UniProtKB:Q9Z207, ECO:0000269|PubMed:18755006, ECO:0000269|PubMed:19457867}.
Mouse PG classificationNA
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