| Gene Information | |
|---|---|
| Gene Name | PP1490 |
| Organism | Homo sapiens (Human) |
| Gene Length | 565 |
| Protein Names | Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UK80 |
| Gene Card | USP21 |
| Uniprot ID | Q9UK80 |
| Pfam | PF00443 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung. {ECO:0000269|PubMed:10799498}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2Y5B (X-ray 2.70A ) 3I3T (X-ray 2.59A ) 3MTN (X-ray 2.70A ) |
| DBSNP | rs34779722 rs17356051 rs1127525 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21888622}. Nucleus {ECO:0000269|PubMed:21888622}. |
| Mouse PG classification | NA |
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