| Gene Information | |
|---|---|
| Gene Name | DHX37 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1157 |
| Protein Names | Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000150990 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8IY37 |
| Gene Card | DHX37 |
| Uniprot ID | Q8IY37 |
| Pfam | PF00270; PF04408; PF00271; PF07717 |
| In ASD | no |
| Allosteric Prediction | no (-1.334220653) |
| Ortholog in Animals | Alpaca_ DHX37 ( ortholog_one2one ) Dog_ DHX37 ( ortholog_one2one ) GuineaPig_ DHX37 ( ortholog_one2one ) Macaque_ DHX37 ( ortholog_one2one ) Mouse_ Dhx37 ( ortholog_one2one ) Pig_ DHX37 ( ortholog_one2one ) Rat_ Dhx37 ( ortholog_one2one ) Rabbit_ DHX37 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | YTHDC2, DHX40, DHX34, DHX32, HELB, DHX57, DHX30, DHX29, DHX36, DHX15, DHX35, DHX9, DHX38, DQX1, DHX16, DHX33, TDRD9, DHX8 |
| Tissue | NA |
| Tissue Specificity | Expressed in the fallopian tube, ovary, uterus and testis. Also expressed in the brain. {ECO:0000269|PubMed:31256877, ECO:0000269|PubMed:31337883}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002682(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7MQA (EM 2.70A ) |
| DBSNP | rs575837056 rs11558556 rs1954619788 rs1384892917 rs1424699115 rs1060499737 rs11057939 rs149331610 rs779613772 rs35165507 rs1954346640 rs1954336215 rs1954336272 rs35016004 rs754186165 rs4516060 rs754141645 rs4447263 rs1277857720 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:30582406, ECO:0000269|PubMed:31337883}. Cytoplasm {ECO:0000269|PubMed:31337883}. Nucleus membrane {ECO:0000269|PubMed:31337883}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |