| Gene Information | |
|---|---|
| Gene Name | INTS11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 600 |
| Protein Names | Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000127054 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q5TA45 |
| Gene Card | INTS11 |
| Uniprot ID | Q5TA45 |
| Pfam | PF10996; PF16661; PF07521 |
| In ASD | no |
| Allosteric Prediction | no (-0.721461912) |
| Ortholog in Animals | Alpaca_ INTS11 ( ortholog_one2one ) Dog_ INTS11 ( ortholog_one2one ) GuineaPig_ INTS11 ( ortholog_one2one ) Macaque_ INTS11 ( ortholog_one2one ) Mouse_ Ints11 ( ortholog_one2one ) Pig_ INTS11 ( ortholog_one2one ) Rat_ Ints11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CPSF2, INTS9, CPSF3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.095000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5V8W (X-ray 2.10A ) 7BFP (EM 3.50A ) 7BFQ (EM 3.50A ) 7CUN (EM 3.50A ) 7PKS (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15684398, ECO:0000269|PubMed:23904267}. Cytoplasm {ECO:0000269|PubMed:15684398, ECO:0000269|PubMed:23904267}. |
| Mouse PG classification | NA |
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