| Gene Information | |
|---|---|
| Gene Name | GPAA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 621 |
| Protein Names | Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000197858 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43292 |
| Gene Card | GPAA1 |
| Uniprot ID | O43292 |
| Pfam | PF04114 |
| In ASD | no |
| Allosteric Prediction | no (-0.438020446) |
| Ortholog in Animals | Alpaca_ GPAA1 ( ortholog_one2one ) Dog_ GPAA1 ( ortholog_one2one ) GuineaPig_ GPAA1 ( ortholog_one2one ) Macaque_ GPAA1 ( ortholog_one2one ) Mouse_ Gpaa1 ( ortholog_one2one ) Pig_ GPAA1 ( ortholog_one2one ) Rat_ Gpaa1 ( ortholog_one2one ) Rabbit_ GPAA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues. {ECO:0000269|PubMed:9468317}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.934500(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7W72 (EM 3.10A ) 7WLD (EM 2.53A ) |
| DBSNP | rs1554763770 rs1554763777 rs782220208 rs1554764058 rs1010907740 rs782768127 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:11483512}; Multi-pass membrane protein {ECO:0000269|PubMed:11483512}. |
| Mouse PG classification | NA |
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