| Gene Information | |
|---|---|
| Gene Name | TRUB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 331 |
| Protein Names | Pseudouridylate synthase TRUB2, mitochondrial (EC 5.4.99.-) (TruB pseudouridine synthase homolog 2) (tRNA pseudouridine 55 synthase TRUB2) (Psi55 synthase TRUB2) (EC 5.4.99.25) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000167112 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95900 |
| Gene Card | TRUB2 |
| Uniprot ID | O95900 |
| Pfam | PF01509 |
| In ASD | no |
| Allosteric Prediction | no (-1.379903241) |
| Ortholog in Animals | Alpaca_ TRUB2 ( ortholog_one2one ) Alpaca_ TRUB2 ( ortholog_one2many ) Dog_ TRUB2 ( ortholog_one2one ) GuineaPig_ TRUB2 ( ortholog_one2one ) Macaque_ TRUB2 ( ortholog_one2one ) Mouse_ Trub2 ( ortholog_one2one ) Pig_ TRUB2 ( ortholog_one2one ) Rat_ Trub2 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001899(Rat);0.020000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2231630 rs2072394 rs2231637 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:27974379, ECO:0000269|PubMed:33023933}. Note=Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly. {ECO:0000269|PubMed:27974379, ECO:0000269|PubMed:28082677}. |
| Mouse PG classification | NA |
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