Gene Information
Gene NameDHX15
OrganismHomo sapiens (Human)
Gene Length795
Protein NamesATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15) (Splicing factor Prp43) (hPrp43)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000109606 )
Evolutionary StageEuk+Bac
AlphaFoldDBO43143
Gene CardDHX15
Uniprot IDO43143
PfamPF00270; PF04408; PF00271; PF07717
In ASDno
Allosteric Predictionno (-1.000146154)
Ortholog in AnimalsAlpaca_ DHX15 ( ortholog_one2one )
Dog_ DHX15 ( ortholog_one2one )
GuineaPig_ DHX15 ( ortholog_one2one )
Macaque_ DHX15 ( ortholog_one2one )
Mouse_ Dhx15 ( ortholog_one2one )
Pig_ DHX15 ( ortholog_one2one )
Rat_ Dhx15 ( ortholog_one2one )
Rabbit_ DHX15 ( ortholog_one2one )
OhnologsNA
ParalogsYTHDC2, DHX40, DHX34, DHX32, HELB, DHX57, DHX30, DHX29, DHX36, DHX35, DHX9, DHX38, DQX1, DHX16, DHX33, TDRD9, DHX8, DHX37
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:9388478}.
Pharmacological Animal Models0.019130(Chimpanzee);0.024514(Mouse);0.003150(Rat);0.065546(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5XDR  (X-ray  2.00A  6ID1  (EM  2.86A  6SH6  (X-ray  1.85A  6SH7  (X-ray  2.21A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:12458796}. Nucleus, nucleolus {ECO:0000269|PubMed:12458796}.
Mouse PG classificationNA
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