| Gene Information | |
|---|---|
| Gene Name | TDRD7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1098 |
| Protein Names | Tudor domain-containing protein 7 (PCTAIRE2-binding protein) (Tudor repeat associator with PCTAIRE-2) (Trap) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000196116 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NHU6 |
| Gene Card | TDRD7 |
| Uniprot ID | Q8NHU6 |
| Pfam | PF12872; PF00567 |
| In ASD | no |
| Allosteric Prediction | no (-0.899800857) |
| Ortholog in Animals | Alpaca_ TDRD7 ( ortholog_one2one ) Dog_ TDRD7 ( ortholog_one2one ) GuineaPig_ TDRD7 ( ortholog_one2one ) Macaque_ TDRD7 ( ortholog_one2one ) Mouse_ Tdrd7 ( ortholog_one2one ) Pig_ TDRD7 ( ortholog_one2one ) Rat_ Tdrd7 ( ortholog_one2one ) Rabbit_ TDRD7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TDRD5, TDRKH, TDRD1, TDRD6, TDRD10, TDRD15 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3RCO (X-ray 1.80A ) |
| DBSNP | rs2045732 rs17852595 rs750207077 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21436445}. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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