| Gene Information | |
|---|---|
| Gene Name | OPN3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 402 |
| Protein Names | Opsin-3 (Encephalopsin) (Panopsin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000054277 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H1Y3 |
| Gene Card | OPN3 |
| Uniprot ID | Q9H1Y3 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-0.144976577) |
| Ortholog in Animals | Alpaca_ OPN3 ( ortholog_one2one ) Dog_ OPN3 ( ortholog_one2one ) GuineaPig_ OPN3 ( ortholog_one2one ) Macaque_ OPN3 ( ortholog_one2one ) Mouse_ Opn3 ( ortholog_one2one ) Rat_ Opn3 ( ortholog_one2one ) |
| Ohnologs | OPN4, OPN5, OPN1SW |
| Paralogs | OPN4, OPN1MW, OPN1SW, OPN1LW, RHO, OPN1MW3, OPN1MW2, RRH, OPN5 |
| Tissue | NA |
| Tissue Specificity | Expressed in tracheal airway smooth muscle (at protein level) (PubMed:30284927). Expressed throughout the epidermis and dermis, predominantly in the basal layer on the facial and abdominal skin (at protein level) (PubMed:30168605). Expressed in dermal fibroblasts (at protein level) (PubMed:31380578). Expressed in melanocytes (at protein level) (PubMed:28842328, PubMed:31097585, PubMed:31730232). Expressed in keratinocytes (PubMed:28842328). Expressed in the retina (PubMed:30284927). {ECO:0000269|PubMed:28842328, ECO:0000269|PubMed:30168605, ECO:0000269|PubMed:30284927, ECO:0000269|PubMed:31097585, ECO:0000269|PubMed:31380578, ECO:0000269|PubMed:31730232}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12072790 rs2273712 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:30168605, ECO:0000269|PubMed:31097585, ECO:0000269|PubMed:31380578, ECO:0000269|PubMed:31730232}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:30168605}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |