| Gene Information | |
|---|---|
| Gene Name | DHPS |
| Organism | Homo sapiens (Human) |
| Gene Length | 369 |
| Protein Names | Deoxyhypusine synthase (DHS) (EC 2.5.1.46) |
| Target Name | deoxyhypusine synthase |
| Target Type | Literature-reported target |
| Gene Age | >4290 ( ENSG00000095059 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P49366 |
| Gene Card | DHPS |
| Uniprot ID | P49366 |
| Pfam | PF01916 |
| In ASD | yes |
| Allosteric Prediction | no (-0.197043887) |
| Ortholog in Animals | Alpaca_ DHPS ( ortholog_one2one ) Dog_ DHPS ( ortholog_one2one ) GuineaPig_ DHPS ( ortholog_one2one ) Macaque_ DHPS ( ortholog_one2one ) Mouse_ Dhps ( ortholog_one2one ) Pig_ DHPS ( ortholog_one2one ) Rat_ Dhps ( ortholog_one2one ) Rabbit_ DHPS ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DHS (X-ray 2.20A ) 1RLZ (X-ray 2.15A ) 1ROZ (X-ray 2.21A ) 1RQD (X-ray 3.00A ) 6P4V (X-ray 1.65A ) 6PGR (X-ray 1.95A ) 6WKZ (X-ray 2.23A ) 6WL6 (X-ray 2.12A ) 6XXH (X-ray 1.52A ) 6XXI (X-ray 1.68A ) 6XXJ (X-ray 1.41A ) 6XXK (X-ray 1.65A ) 6XXL (X-ray 1.69A ) 6XXM (X-ray 1.67A ) 7A6S (X-ray 1.75A ) 7A6T (X-ray 1.66A ) |
| DBSNP | rs758100382 rs10425108 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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