| Gene Information | |
|---|---|
| Gene Name | ANKS4B |
| Organism | Homo sapiens (Human) |
| Gene Length | 417 |
| Protein Names | Ankyrin repeat and SAM domain-containing protein 4B (Harmonin-interacting ankyrin repeat-containing protein) (Harp) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000175311 ) 3 ( ENSG00000284290 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N8V4 |
| Gene Card | ANKS4B |
| Uniprot ID | Q8N8V4 |
| Pfam | PF12796; PF00536 |
| In ASD | no |
| Allosteric Prediction | no (-1.71613864) |
| Ortholog in Animals | Alpaca_ ANKS4B ( ortholog_one2one ) Dog_ ANKS4B ( ortholog_one2one ) GuineaPig_ ANKS4B ( ortholog_one2one ) Macaque_ ANKS4B ( ortholog_one2one ) Mouse_ Anks4b ( ortholog_one2one ) Pig_ ANKS4B ( ortholog_one2one ) Rat_ Anks4b ( ortholog_one2one ) Rabbit_ ANKS4B ( ortholog_one2one ) |
| Ohnologs | USH1G |
| Paralogs | USH1G |
| Tissue | appendix, colon, gall.bladder, kidney, small.intestine |
| Tissue Specificity | Expressed in kidney and small intestine. {ECO:0000269|PubMed:12588794}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell projection, microvillus {ECO:0000269|PubMed:26812018}. Note=Localizes at the tip of microvilli (PubMed:26812018). May associate with endoplasmic reticulum membranes (By similarity). {ECO:0000250|UniProtKB:Q8K3X6, ECO:0000269|PubMed:26812018}. |
| Mouse PG classification | NA |
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