| Gene Information | |
|---|---|
| Gene Name | DGUOK |
| Organism | Homo sapiens (Human) |
| Gene Length | 277 |
| Protein Names | Deoxyguanosine kinase, mitochondrial (EC 2.7.1.113) (Deoxyadenosine kinase, mitochondrial) (EC 2.7.1.76) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000114956 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q16854 |
| Gene Card | DGUOK |
| Uniprot ID | Q16854 |
| Pfam | PF01712 |
| In ASD | no |
| Allosteric Prediction | yes (0.52623511) |
| Ortholog in Animals | Alpaca_ DGUOK ( ortholog_one2one ) Dog_ DGUOK ( ortholog_one2one ) GuineaPig_ DGUOK ( ortholog_one2one ) Macaque_ DGUOK ( ortholog_one2one ) Mouse_ Dguok ( ortholog_one2one ) Pig_ DGUOK ( ortholog_one2one ) Rat_ Dguok ( ortholog_one2one ) Rabbit_ DGUOK ( ortholog_one2one ) |
| Ohnologs | DCK |
| Paralogs | DCK, NDUFA10, TK2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highest expression in muscle, brain, liver and lymphoid tissues. {ECO:0000269|PubMed:8706825}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OCP (X-ray 2.80A ) |
| DBSNP | rs762550967 rs763615602 rs104893631 rs144181978 rs74874677 rs104893632 rs749464475 rs886037846 |
| Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:Q9QX60}. |
| Mouse PG classification | NA |
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