| Gene Information | |
|---|---|
| Gene Name | DGKG |
| Organism | Homo sapiens (Human) |
| Gene Length | 791 |
| Protein Names | Diacylglycerol kinase gamma (DAG kinase gamma) (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) |
| Target Name | diacylglycerol kinase |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000058866 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49619 |
| Gene Card | DGKG |
| Uniprot ID | P49619 |
| Pfam | PF00130; PF14513; PF00609; PF00781 |
| In ASD | no |
| Allosteric Prediction | no (-0.242116517) |
| Ortholog in Animals | Alpaca_ DGKG ( ortholog_one2one ) Dog_ DGKG ( ortholog_one2one ) GuineaPig_ DGKG ( ortholog_one2one ) Macaque_ DGKG ( ortholog_one2one ) Mouse_ Dgkg ( ortholog_one2one ) Pig_ DGKG ( ortholog_one2one ) Rat_ Dgkg ( ortholog_one2one ) Rabbit_ DGKG ( ortholog_one2one ) |
| Ohnologs | DGKA, DGKB |
| Paralogs | DGKQ, DGKE, DGKH, DGKI, DGKB, DGKD, DGKA, DGKK, DGKZ |
| Tissue | cerebellar.hemisphere, cerebellum, esophagus.muscularis.mucosa, gastroesophageal.junction |
| Tissue Specificity | Predominantly expressed in retina and in a much lesser extent in the brain. Other tissues contain extremely low levels of DGK-gamma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1004588 rs2193587 rs3213770 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:8034597}. Cytoplasm, cytosol {ECO:0000269|PubMed:8034597}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P49620}. |
| Mouse PG classification | NA |
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