| Gene Information | |
|---|---|
| Gene Name | DGA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 328 |
| Protein Names | Acyl-CoA wax alcohol acyltransferase 1 (EC 2.3.1.75) (Diacylglycerol O-acyltransferase 2-like protein 3) (Diacylglycerol acyltransferase 2) (Long-chain-alcohol O-fatty-acyltransferase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q58HT5 |
| Gene Card | AWAT1 |
| Uniprot ID | Q58HT5 |
| Pfam | PF03982 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in skin, where it is limited to the sebaceous gland. Expressed in more mature, centrally located cells just before their rupture and sebum release. Also expressed in all tissues except spleen. Expressed at higher level in thymus, prostate and testis. {ECO:0000269|PubMed:15671038}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q6E213}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |