| Gene Information | |
|---|---|
| Gene Name | DFFB |
| Organism | Homo sapiens (Human) |
| Gene Length | 338 |
| Protein Names | DNA fragmentation factor subunit beta (EC 3.-.-.-) (Caspase-activated deoxyribonuclease) (CAD) (Caspase-activated DNase) (Caspase-activated nuclease) (CPAN) (DNA fragmentation factor 40 kDa subunit) (DFF-40) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000169598 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O76075 |
| Gene Card | DFFB |
| Uniprot ID | O76075 |
| Pfam | PF02017; PF09230 |
| In ASD | no |
| Allosteric Prediction | no (-0.154219492) |
| Ortholog in Animals | Alpaca_ DFFB ( ortholog_one2one ) Dog_ DFFB ( ortholog_one2one ) GuineaPig_ DFFB ( ortholog_one2one ) Macaque_ DFFB ( ortholog_one2one ) Mouse_ Dffb ( ortholog_one2one ) Pig_ DFFB ( ortholog_one2one ) Rat_ Dffb ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1IBX (NMR - ) |
| DBSNP | rs12738235 rs12564400 |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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