| Gene Information | |
|---|---|
| Gene Name | PPP3CC |
| Organism | Homo sapiens (Human) |
| Gene Length | 512 |
| Protein Names | Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin, testis-specific catalytic subunit) (Calmodulin-dependent calcineurin A subunit gamma isoform) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000120910 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P48454 |
| Gene Card | PPP3CC |
| Uniprot ID | P48454 |
| Pfam | PF00149 |
| In ASD | no |
| Allosteric Prediction | yes (0.522400543) |
| Ortholog in Animals | Alpaca_ PPP3CC ( ortholog_one2one ) Dog_ PPP3CC ( ortholog_one2one ) GuineaPig_ PPP3CC ( ortholog_one2one ) Macaque_ PPP3CC ( ortholog_one2one ) Mouse_ Ppp3cc ( ortholog_one2one ) Pig_ PPP3CC ( ortholog_one2one ) Rat_ Ppp3cc ( ortholog_one2one ) Rabbit_ PPP3CC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPP6C, PPP5C, PPP2CB, PPP2CA, PPEF2, PPP4C, PPP3CA, PPEF1, PPP1CA, PPP1CC, PPP1CB, PPP3CB |
| Tissue | NA |
| Tissue Specificity | Testis. {ECO:0000269|PubMed:1339277}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7U0T (X-ray 2.45A ) |
| DBSNP | rs28764007 |
| Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:P48455}. Note=Localizes in the mitochondria in a SPATA33-dependent manner. {ECO:0000250|UniProtKB:P48455}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |