| Gene Information | |
|---|---|
| Gene Name | DER1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 251 |
| Protein Names | Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BUN8 |
| Gene Card | DERL1 |
| Uniprot ID | Q9BUN8 |
| Pfam | PF04511 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15215855, ECO:0000269|PubMed:16449189}. |
| Pharmacological Animal Models | 0.142055(Chimpanzee);0.029297(Mouse);0.004136(Rat);0.015385(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5GLF (X-ray 2.25A ) 7CZB (EM 3.80A ) |
| DBSNP | rs2272722 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15215855, ECO:0000269|PubMed:15215856, ECO:0000269|PubMed:16186509, ECO:0000269|PubMed:16449189}; Multi-pass membrane protein {ECO:0000269|PubMed:15215855, ECO:0000269|PubMed:15215856, ECO:0000269|PubMed:16186509, ECO:0000269|PubMed:16449189}. |
| Mouse PG classification | NA |
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