| Gene Information | |
|---|---|
| Gene Name | DEPDC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1606 |
| Protein Names | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q70Z35 |
| Gene Card | PREX2 |
| Uniprot ID | Q70Z35 |
| Pfam | PF00610; PF00169; PF00621 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart. {ECO:0000269|PubMed:15304343}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6BNM (X-ray 1.90A ) |
| DBSNP | rs11784582 rs147538692 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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