| Gene Information | |
|---|---|
| Gene Name | QRICH2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1663 |
| Protein Names | Glutamine-rich protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000129646 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H0J4 |
| Gene Card | QRICH2 |
| Uniprot ID | Q9H0J4 |
| Pfam | PF16043 |
| In ASD | no |
| Allosteric Prediction | no (-1.417247932) |
| Ortholog in Animals | Alpaca_ QRICH2 ( ortholog_one2one ) Macaque_ QRICH2 ( ortholog_one2one ) Mouse_ Qrich2 ( ortholog_one2one ) Pig_ QRICH2 ( ortholog_one2one ) Rat_ Qrich2 ( ortholog_one2one ) Rabbit_ QRICH2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZP4, ZP1, C16orf96, ZP2 |
| Tissue | testis |
| Tissue Specificity | Expressed in the sperm. {ECO:0000269|PubMed:30683861}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6501880 rs6501878 rs6501879 rs6501874 rs2279054 rs2279053 rs2279052 rs757438651 rs775768893 rs144208097 |
| Subcellular location [CC] | Nucleus membrane {ECO:0000250|UniProtKB:Q3V2A7}. Nucleus {ECO:0000250|UniProtKB:Q3V2A7}. Cytoplasm {ECO:0000250|UniProtKB:Q3V2A7}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:30683861}. Note=Localization varies during spermatozoa development. The protein is distributed in the nuclear membrane of the spermatogonia, in the nucleus of round spermatids, in the nucleus and cytoplasm of early elongating spermatids, in the cytoplasm of late elongating spermatids, and in the flagella of epididymal spermatozoa. {ECO:0000250|UniProtKB:Q3V2A7}. |
| Mouse PG classification | NA |
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