| Gene Information | |
|---|---|
| Gene Name | S100A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 94 |
| Protein Names | Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1) |
| Target Name | protein s100-a1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000160678 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P23297 |
| Gene Card | S100A1 |
| Uniprot ID | P23297 |
| Pfam | PF00036; PF01023 |
| In ASD | no |
| Allosteric Prediction | no (-0.285730056) |
| Ortholog in Animals | Alpaca_ S100A1 ( ortholog_one2one ) Dog_ S100A1 ( ortholog_one2one ) GuineaPig_ S100A1 ( ortholog_one2one ) Macaque_ S100A1 ( ortholog_one2one ) Mouse_ S100a1 ( ortholog_one2one ) Pig_ S100A1 ( ortholog_one2one ) Rat_ S100a1 ( ortholog_one2one ) Rabbit_ S100A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | S100A3, S100A10, S100A4, SNTN, S100A8, S100A13, S100A11, S100A5, S100B, S100A14, S100A16, S100Z, S100A12, S100P, S100G, S100A2, S100A7, S100A7A, CRNN, S100A9, S100A6 |
| Tissue | heart, skeletal.muscle |
| Tissue Specificity | Highly prevalent in heart (PubMed:12804600, PubMed:1384693). Also found in lesser quantities in skeletal muscle and brain (PubMed:1384693). {ECO:0000269|PubMed:12804600, ECO:0000269|PubMed:1384693}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.125965(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2L0P (NMR - ) 2LHL (NMR - ) 2LLS (NMR - ) 2LLT (NMR - ) 2LLU (NMR - ) 2LP2 (NMR - ) 2LP3 (NMR - ) 2LUX (NMR - ) 2M3W (NMR - ) 5K89 (X-ray 2.25A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15171681}. Sarcoplasmic reticulum {ECO:0000269|PubMed:12804600}. Mitochondrion {ECO:0000250|UniProtKB:P56565}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |