| Gene Information | |
|---|---|
| Gene Name | DENND2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1009 |
| Protein Names | DENN domain-containing protein 2A |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000146966 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9ULE3 |
| Gene Card | DENND2A |
| Uniprot ID | Q9ULE3 |
| Pfam | PF03455; PF02141; PF03456 |
| In ASD | no |
| Allosteric Prediction | no (-1.569771973) |
| Ortholog in Animals | Alpaca_ DENND2A ( ortholog_one2one ) Alpaca_ DENND2A ( ortholog_one2many ) Dog_ DENND2A ( ortholog_one2one ) GuineaPig_ DENND2A ( ortholog_one2one ) Macaque_ DENND2A ( ortholog_one2one ) Mouse_ Dennd2a ( ortholog_one2one ) Pig_ DENND2A ( ortholog_one2one ) Rat_ Dennd2a ( ortholog_one2one ) Rabbit_ DENND2A ( ortholog_one2one ) |
| Ohnologs | DENND2B, DENND2D, DENND2C |
| Paralogs | DENND2C, DENND2B, DENND2D |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs269243 rs2293177 rs6464833 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20937701}. Note=Associated with actin filaments. |
| Mouse PG classification | NA |
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