| Gene Information | |
|---|---|
| Gene Name | DENND1A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1009 |
| Protein Names | DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Protein FAM31A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000119522 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TEH3 |
| Gene Card | DENND1A |
| Uniprot ID | Q8TEH3 |
| Pfam | PF03455; PF02141; PF03456 |
| In ASD | no |
| Allosteric Prediction | no (-0.301906437) |
| Ortholog in Animals | Alpaca_ DENND1A ( ortholog_one2one ) Dog_ DENND1A ( ortholog_one2one ) GuineaPig_ DENND1A ( ortholog_one2one ) Macaque_ DENND1A ( ortholog_one2one ) Mouse_ Dennd1a ( ortholog_one2one ) Pig_ DENND1A ( ortholog_one2one ) Rat_ Dennd1a ( ortholog_one2one ) Rabbit_ DENND1A ( ortholog_one2one ) |
| Ohnologs | DENND1C |
| Paralogs | DENND1C, DENND1B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6EKK (X-ray 1.82A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000269|PubMed:20154091, ECO:0000269|PubMed:20937701}; Peripheral membrane protein {ECO:0000269|PubMed:20937701}. Presynaptic cell membrane {ECO:0000269|PubMed:20937701}. Note=Associates to membranes via lipid-binding activity. {ECO:0000250|UniProtKB:Q8K382}. |
| Mouse PG classification | NA |
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