| Gene Information | |
|---|---|
| Gene Name | DEFB121 |
| Organism | Homo sapiens (Human) |
| Gene Length | 76 |
| Protein Names | Beta-defensin 121 (Beta-defensin 21) (DEFB-21) (Defensin, beta 121) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000204548 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q5J5C9 |
| Gene Card | DEFB121 |
| Uniprot ID | Q5J5C9 |
| Pfam | PF13841 |
| In ASD | no |
| Allosteric Prediction | no (-1.381795032) |
| Ortholog in Animals | Alpaca_ DEFB121 ( ortholog_one2one ) Dog_ DEFB121 ( ortholog_one2one ) Macaque_ DEFB121 ( ortholog_one2one ) Mouse_ Defb22 ( ortholog_many2many ) Pig_ DEFB121 ( ortholog_one2one ) Rat_ Defb22 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | DEFB116, DEFB108B, DEFB125, DEFB118, DEFB134, DEFB128, DEFB115, DEFB132, DEFB119, DEFB129, DEFB127, DEFB135, DEFB104B, DEFB104A, DEFB123, DEFB124, DEFB131A, DEFB131B |
| Tissue | NA |
| Tissue Specificity | Abundant expression in the male reproductive tract only. {ECO:0000269|PubMed:15772680}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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