| Gene Information | |
|---|---|
| Gene Name | FAM161A |
| Organism | Homo sapiens (Human) |
| Gene Length | 660 |
| Protein Names | Protein FAM161A |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000170264 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q3B820 |
| Gene Card | FAM161A |
| Uniprot ID | Q3B820 |
| Pfam | PF10595 |
| In ASD | no |
| Allosteric Prediction | no (-1.522584493) |
| Ortholog in Animals | Alpaca_ FAM161A ( ortholog_one2one ) Dog_ FAM161A ( ortholog_one2one ) GuineaPig_ FAM161A ( ortholog_one2one ) Macaque_ FAM161A ( ortholog_one2one ) Mouse_ Fam161a ( ortholog_one2one ) Pig_ FAM161A ( ortholog_one2one ) Rat_ Fam161a ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TSGA10IP, FAM161B |
| Tissue | NA |
| Tissue Specificity | Isoform 1 and isoform 3 are widely expressed with highest levels in retina and testis, with isoform 1 being the most abundant in all tissues tested. {ECO:0000269|PubMed:20705278, ECO:0000269|PubMed:20705279}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11125895 rs17513722 rs6733774 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:22940612}. Cell projection, cilium {ECO:0000269|PubMed:22940612}. Note=Localized to the region between the outer and inner photoreceptor segments, corresponding to the photoreceptor connecting cilium. |
| Mouse PG classification | HPG |
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