| Gene Information | |
|---|---|
| Gene Name | DECR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 335 |
| Protein Names | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1) |
| Target Name | 2,4-dienoyl-coa reductase, mitochondrial |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000104325 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q16698 |
| Gene Card | DECR1 |
| Uniprot ID | Q16698 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.193222985) |
| Ortholog in Animals | Alpaca_ DECR1 ( ortholog_one2one ) Dog_ DECR1 ( ortholog_one2one ) GuineaPig_ DECR1 ( ortholog_one2one ) Macaque_ DECR1 ( ortholog_one2one ) Mouse_ Decr1 ( ortholog_one2one ) Pig_ DECR1 ( ortholog_one2one ) Rat_ Decr1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DECR2 |
| Tissue | NA |
| Tissue Specificity | Heart = liver = pancreas > kidney >> skeletal muscle = lung. {ECO:0000269|PubMed:7818482}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1W6U (X-ray 1.75A ) 1W73 (X-ray 2.10A ) 1W8D (X-ray 2.20A ) |
| DBSNP | rs15094 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:7818482}. |
| Mouse PG classification | NA |
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