| Gene Information | |
|---|---|
| Gene Name | CDHR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 859 |
| Protein Names | Cadherin-related family member 1 (Photoreceptor cadherin) (prCAD) (Protocadherin-21) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000148600 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96JP9 |
| Gene Card | CDHR1 |
| Uniprot ID | Q96JP9 |
| Pfam | PF00028 |
| In ASD | no |
| Allosteric Prediction | no (-1.51062528) |
| Ortholog in Animals | Alpaca_ CDHR1 ( ortholog_one2one ) Dog_ CDHR1 ( ortholog_one2one ) GuineaPig_ CDHR1 ( ortholog_one2one ) Macaque_ CDHR1 ( ortholog_one2one ) Mouse_ Cdhr1 ( ortholog_one2one ) Pig_ CDHR1 ( ortholog_one2one ) Rat_ Cdhr1 ( ortholog_one2one ) Rabbit_ CDHR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CDH7, CDH9, CDH20, CDH4, CDH18, PCDH1, PCDH20, CDH26, CDH19, PCDH9, CDH3, PCDH11Y, PCDH11X, CDH17, CDHR5, CDHR3, DCHS2, CDH24, CDH23, PCDH7, CDH15, DCHS1, CDH11, CDH8, CDH10, CDH12, CDH13, CDH6, CDH1, CDHR2, CDH22, CDH5, CDH2 |
| Tissue | skin, colon, pineal.gland, zone.of.skin, sigmoid.colon, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12781048 rs759855253 rs200880106 rs7086200 rs143662988 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Localized at the junction between the inner and outer segments of rod and cone photoreceptors cells. Confined to the base of the OS. Localized on the edges of nascent evaginating disks on the side of the OS opposite the connecting cilium. Expressed at postnatal day 2 at the apical tip of the rod photoreceptor cells, the site of the developing OS. Colocalized with rhodopsin between postnatal days 2 and 9 at the base of the growing OS region (By similarity). {ECO:0000250}. |
| Mouse PG classification | HPG |
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