| Gene Information | |
|---|---|
| Gene Name | DDX46 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1031 |
| Protein Names | Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46) (PRP5 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000145833 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7L014 |
| Gene Card | DDX46 |
| Uniprot ID | Q7L014 |
| Pfam | PF00270; PF00271 |
| In ASD | no |
| Allosteric Prediction | no (-0.533939612) |
| Ortholog in Animals | Alpaca_ DDX46 ( ortholog_one2one ) Dog_ DDX46 ( ortholog_one2one ) GuineaPig_ DDX46 ( ortholog_one2one ) Macaque_ DDX46 ( ortholog_one2many ) Mouse_ Ddx46 ( ortholog_one2one ) Pig_ DDX46 ( ortholog_one2one ) Rat_ Ddx46 ( ortholog_one2one ) Rabbit_ DDX46 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DDX28, DDX42, DDX25, DDX47, DDX49, DDX20, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, EIF4A1, DDX6, DDX39A, DDX55, DDX18, DDX21, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, DDX43, EIF4A2, DDX27 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6Y50 (EM 4.10A ) 6Y53 (EM 7.10A ) 6Y5Q (EM 7.10A ) 7Q3L (EM 2.30A ) |
| DBSNP | rs10447293 |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:12234937}. Nucleus, Cajal body {ECO:0000269|PubMed:12234937}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Note=Present in Cajal bodies (CBs) and nuclear speckles. |
| Mouse PG classification | NA |
| click here to return to the previous page | |