| Gene Information | |
|---|---|
| Gene Name | DDX39A |
| Organism | Homo sapiens (Human) |
| Gene Length | 427 |
| Protein Names | ATP-dependent RNA helicase DDX39A (EC 3.6.4.13) (DEAD box protein 39) (Nuclear RNA helicase URH49) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000123136 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O00148 |
| Gene Card | DDX39A |
| Uniprot ID | O00148 |
| Pfam | PF00270; PF00271 |
| In ASD | no |
| Allosteric Prediction | no (-0.953287124) |
| Ortholog in Animals | Alpaca_ DDX39A ( ortholog_one2many ) Dog_ DDX39A ( ortholog_one2one ) GuineaPig_ DDX39A ( ortholog_one2one ) Macaque_ DDX39A ( ortholog_one2one ) Mouse_ Ddx39a ( ortholog_one2one ) Pig_ DDX39A ( ortholog_one2one ) Rat_ Ddx39a ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DDX28, DDX42, DDX25, DDX47, DDX49, DDX20, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, EIF4A1, DDX6, DDX55, DDX18, DDX21, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, DDX43, EIF4A2, DDX27, DDX46 |
| Tissue | NA |
| Tissue Specificity | Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland. {ECO:0000269|PubMed:15047853}. |
| Pharmacological Animal Models | 0.080853(Chimpanzee);0.053752(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs36127505 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21859714}. Cytoplasm {ECO:0000269|PubMed:21859714}. Note=Can translocate to the cytoplasm in the presence of MX1. |
| Mouse PG classification | NA |
| click here to return to the previous page | |