Gene Information | |
---|---|
Gene Name | DDX28 |
Organism | Homo sapiens (Human) |
Gene Length | 540 |
Protein Names | Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28) |
Target Name | NA |
Target Type | NA |
Gene Age | 18 ( ENSG00000182810 ) |
Evolutionary Stage | Euk+Bac |
AlphaFoldDB | Q9NUL7 |
Gene Card | DDX28 |
Uniprot ID | Q9NUL7 |
Pfam | PF00270; PF00271 |
In ASD | no |
Allosteric Prediction | no (-1.754020806) |
Ortholog in Animals | Alpaca_ DDX28 ( ortholog_one2one ) Dog_ DDX28 ( ortholog_one2one ) GuineaPig_ DDX28 ( ortholog_one2one ) Macaque_ DDX28 ( ortholog_one2one ) Mouse_ Ddx28 ( ortholog_one2one ) Pig_ DDX28 ( ortholog_one2one ) Rat_ Ddx28 ( ortholog_one2one ) Rabbit_ DDX28 ( ortholog_one2one ) |
Ohnologs | NA |
Paralogs | DDX42, DDX25, DDX47, DDX49, DDX20, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, EIF4A1, DDX6, DDX39A, DDX55, DDX18, DDX21, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, DDX43, EIF4A2, DDX27, DDX46 |
Tissue | NA |
Tissue Specificity | Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate. {ECO:0000269|PubMed:11350955}. |
Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001516(Rat);0.03(Rabbit) |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 7OI6 (EM 5.70A ) |
DBSNP | rs237831 |
Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11350955, ECO:0000269|PubMed:25683708}. Mitochondrion {ECO:0000269|PubMed:11350955}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:25683715}. Mitochondrion matrix {ECO:0000269|PubMed:25683708}. Note=Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription. Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. {ECO:0000269|PubMed:25683708, ECO:0000269|PubMed:25683715}. |
Mouse PG classification | NA |
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