| Gene Information | |
|---|---|
| Gene Name | DDX20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 824 |
| Protein Names | Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000064703 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UHI6 |
| Gene Card | DDX20 |
| Uniprot ID | Q9UHI6 |
| Pfam | PF00270; PF00271 |
| In ASD | no |
| Allosteric Prediction | no (-0.242583938) |
| Ortholog in Animals | Alpaca_ DDX20 ( ortholog_one2one ) Dog_ DDX20 ( ortholog_one2one ) GuineaPig_ DDX20 ( ortholog_one2one ) Macaque_ DDX20 ( ortholog_one2one ) Mouse_ Ddx20 ( ortholog_one2one ) Pig_ DDX20 ( ortholog_one2one ) Rat_ Ddx20 ( ortholog_one2one ) Rabbit_ DDX20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DDX28, DDX42, DDX25, DDX47, DDX49, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, EIF4A1, DDX6, DDX39A, DDX55, DDX18, DDX21, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, DDX43, EIF4A2, DDX27, DDX46 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.012598(Rat);0.086957(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OXC (X-ray 1.30A ) 3B7G (X-ray 1.90A ) |
| DBSNP | rs197412 rs197414 rs85276 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10601333, ECO:0000305|PubMed:12095920}. Nucleus, gem {ECO:0000269|PubMed:10601333, ECO:0000305|PubMed:10383418}. Note=Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems). {ECO:0000269|PubMed:10601333}. |
| Mouse PG classification | NA |
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