| Gene Information | |
|---|---|
| Gene Name | DDT |
| Organism | Homo sapiens (Human) |
| Gene Length | 118 |
| Protein Names | D-dopachrome decarboxylase (EC 4.1.1.84) (D-dopachrome tautomerase) (Phenylpyruvate tautomerase II) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000099977 ) 3 ( ENSG00000275003 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P30046 |
| Gene Card | DDT |
| Uniprot ID | P30046 |
| Pfam | PF01187 |
| In ASD | no |
| Allosteric Prediction | no (-1.098795129) |
| Ortholog in Animals | Mouse_ Ddt ( ortholog_one2many ) Pig_ DDT ( ortholog_one2many ) Rat_ Ddt ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | DDTL, MIF |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the liver and at lower levels in the heart, lung and pancreas. {ECO:0000269|PubMed:8267597, ECO:0000269|PubMed:9480844}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DPT (X-ray 1.54A ) 3KAN (X-ray 1.13A ) 4Q3F (X-ray 1.80A ) 6C5F (X-ray 1.40A ) 7MRU (X-ray 1.33A ) 7MRV (X-ray 1.57A ) 7MSE (X-ray 1.27A ) 7MW7 (X-ray 1.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000305|PubMed:8267597}. |
| Mouse PG classification | NA |
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