| Gene Information | |
|---|---|
| Gene Name | DDN |
| Organism | Homo sapiens (Human) |
| Gene Length | 711 |
| Protein Names | Dendrin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000181418 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O94850 |
| Gene Card | DDN |
| Uniprot ID | O94850 |
| Pfam | PF15498 |
| In ASD | no |
| Allosteric Prediction | no (-1.135344751) |
| Ortholog in Animals | Alpaca_ DDN ( ortholog_one2one ) Dog_ DDN ( ortholog_one2one ) GuineaPig_ DDN ( ortholog_one2one ) Macaque_ DDN ( ortholog_one2one ) Mouse_ Ddn ( ortholog_one2one ) Pig_ DDN ( ortholog_one2one ) Rat_ Ddn ( ortholog_one2one ) Rabbit_ DDN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | brain, cerebral.cortex, kidney, amygdala, caudate.nucleus, hippocampus, nucleus.accumbens, putamen, skeletal.muscle |
| Tissue Specificity | Specifically expressed in brain and kidney. Expressed in kidney glomerular capillary loops (at protein level). {ECO:0000269|PubMed:17251388, ECO:0000269|PubMed:18356187}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10783299 |
| Subcellular location [CC] | Cell projection, dendritic spine membrane; Peripheral membrane protein. Cytoplasm. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Perikaryon {ECO:0000250}. Nucleus {ECO:0000250}. Note=Enriched at the cytoplasmic insertion of the slit diaphragm into the foot process of podocytes and associated with polyribosomes in dendrites. {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |