| Gene Information | |
|---|---|
| Gene Name | DDH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.210) (EC 1.1.1.357) (EC 1.1.1.51) (EC 1.1.1.53) (EC 1.1.1.62) (EC 1.3.1.20) (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (EC 1.1.1.149) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1) (DD1) (High-affinity hepatic bile acid-binding protein) (HBAB) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q04828 |
| Gene Card | AKR1C1 |
| Uniprot ID | Q04828 |
| Pfam | PF00248 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain. {ECO:0000269|PubMed:10998348, ECO:0000269|PubMed:11013348}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1MRQ (X-ray 1.59A ) 3C3U (X-ray 1.80A ) 3GUG (X-ray 1.90A ) 3NTY (X-ray 1.87A ) 4YVP (X-ray 2.60A ) 6A7A (X-ray 2.37A ) 6IJX (X-ray 2.20A ) |
| DBSNP | rs139588200 rs760575583 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:8486699}. |
| Mouse PG classification | NA |
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