Gene Information
Gene NameTNNI1
OrganismHomo sapiens (Human)
Gene Length187
Protein NamesTroponin I, slow skeletal muscle (Troponin I, slow-twitch isoform)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000159173 )
Evolutionary StageEumetazoa
AlphaFoldDBP19237
Gene CardTNNI1
Uniprot IDP19237
PfamPF00992
In ASDno
Allosteric Predictionno (-0.955412584)
Ortholog in AnimalsAlpaca_ TNNI1 ( ortholog_one2one )
Dog_ TNNI1 ( ortholog_one2one )
GuineaPig_ TNNI1 ( ortholog_one2one )
Macaque_ TNNI1 ( ortholog_one2one )
Mouse_ Tnni1 ( ortholog_one2one )
Pig_ TNNI1 ( ortholog_one2one )
Rat_ Tnni1 ( ortholog_one2one )
Rabbit_ TNNI1 ( ortholog_one2one )
OhnologsTNNI2
ParalogsTNNI2, TNNI3
Tissueesophagus, prostate, skeletal.muscle, heart
Tissue SpecificityHighest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes. {ECO:0000269|PubMed:2365354, ECO:0000269|PubMed:8144655}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.046154(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2296695 
Subcellular location [CC]NA
Mouse PG classificationNA
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