| Gene Information | |
|---|---|
| Gene Name | HACL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 578 |
| Protein Names | 2-hydroxyacyl-CoA lyase 1 (EC 4.1.2.63) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000131373 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UJ83 |
| Gene Card | HACL1 |
| Uniprot ID | Q9UJ83 |
| Pfam | PF02775; PF00205; PF02776 |
| In ASD | no |
| Allosteric Prediction | no (-0.651748334) |
| Ortholog in Animals | Alpaca_ HACL1 ( ortholog_one2one ) GuineaPig_ HACL1 ( ortholog_one2one ) Macaque_ HACL1 ( ortholog_one2one ) Mouse_ Hacl1 ( ortholog_one2one ) Pig_ HACL1 ( ortholog_one2one ) Rat_ Hacl1 ( ortholog_one2one ) Rabbit_ HACL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ILVBL |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10468558, ECO:0000269|PubMed:28289220}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Peroxisome {ECO:0000269|PubMed:10468558, ECO:0000269|PubMed:21708296, ECO:0000269|PubMed:28289220}. |
| Mouse PG classification | NA |
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