| Gene Information | |
|---|---|
| Gene Name | DCS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 337 |
| Protein Names | m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96C86 |
| Gene Card | DCPS |
| Uniprot ID | Q96C86 |
| Pfam | PF05652 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in liver, brain, kidney, testis and prostate. {ECO:0000269|PubMed:12871939}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ST0 (X-ray 1.90A ) 1ST4 (X-ray 2.02A ) 1XML (X-ray 2.00A ) 1XMM (X-ray 2.50A ) 3BL7 (X-ray 2.31A ) 3BL9 (X-ray 1.80A ) 3BLA (X-ray 2.60A ) 4QDE (X-ray 2.90A ) 4QDV (X-ray 2.80A ) 4QEB (X-ray 3.21A ) 5OSY (X-ray 2.06A ) |
| DBSNP | rs11557735 rs137941190 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Note=Predominantly localized in the nucleus. Nucleocytoplasmic shuttling protein that can transiently enter the cytoplasm in mammalian cells in a XPO1/CRM1-dependent manner. |
| Mouse PG classification | NA |
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