| Gene Information | |
|---|---|
| Gene Name | DCP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 420 |
| Protein Names | m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 20) (Nudix motif 20) (mRNA-decapping enzyme 2) (hDpc) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000172795 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IU60 |
| Gene Card | DCP2 |
| Uniprot ID | Q8IU60 |
| Pfam | PF05026; PF00293 |
| In ASD | no |
| Allosteric Prediction | no (-0.881727685) |
| Ortholog in Animals | Alpaca_ DCP2 ( ortholog_one2one ) Dog_ DCP2 ( ortholog_one2one ) GuineaPig_ DCP2 ( ortholog_one2one ) Macaque_ DCP2 ( ortholog_one2one ) Mouse_ Dcp2 ( ortholog_one2one ) Pig_ DCP2 ( ortholog_one2one ) Rat_ Dcp2 ( ortholog_one2one ) Rabbit_ DCP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in brain and testis. Not detected in heart (at protein level). {ECO:0000269|PubMed:21070968}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.07319(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5MP0 (X-ray 1.63A ) 5QOH (X-ray 1.93A ) 5QOI (X-ray 1.99A ) 5QOJ (X-ray 2.05A ) 5QOK (X-ray 2.28A ) 5QOL (X-ray 1.85A ) 5QOM (X-ray 1.87A ) 5QON (X-ray 1.80A ) 5QOO (X-ray 1.56A ) 5QOP (X-ray 1.86A ) 5QOQ (X-ray 1.49A ) 5QOR (X-ray 1.95A ) 5QOS (X-ray 1.70A ) 5QOT (X-ray 1.68A ) 5QOU (X-ray 2.19A ) 5QOV (X-ray 1.65A ) 5QOW (X-ray 1.82A ) 5QOX (X-ray 1.95A ) 5QOY (X-ray 1.69A ) 5QOZ (X-ray 1.70A ) 5QP0 (X-ray 2.00A ) 5QP1 (X-ray 1.79A ) 5QP2 (X-ray 1.83A ) 5QP3 (X-ray 1.75A ) 5QP4 (X-ray 1.71A ) 5QP5 (X-ray 1.90A ) 5QP6 (X-ray 1.65A ) 5QP7 (X-ray 1.88A ) 5QP8 (X-ray 1.64A ) 5QP9 (X-ray 1.72A ) 5QPA (X-ray 1.61A ) 5QPB (X-ray 1.68A ) 5QPC (X-ray 1.66A ) |
| DBSNP | rs33555 |
| Subcellular location [CC] | Cytoplasm, P-body {ECO:0000269|PubMed:15067023, ECO:0000269|PubMed:15273322, ECO:0000269|PubMed:16364915, ECO:0000269|PubMed:20616046}. Nucleus {ECO:0000269|PubMed:15273322}. Note=Predominantly cytoplasmic, in processing bodies (PB) (PubMed:15273322). A minor amount is nuclear (PubMed:15273322). {ECO:0000269|PubMed:15273322, ECO:0000269|PubMed:16364915, ECO:0000269|PubMed:20616046}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |