| Gene Information | |
|---|---|
| Gene Name | TARS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 723 |
| Protein Names | Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000113407 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P26639 |
| Gene Card | TARS1 |
| Uniprot ID | P26639 |
| Pfam | PF03129; PF02824; PF00587; PF07973 |
| In ASD | no |
| Allosteric Prediction | yes (0.580078619) |
| Ortholog in Animals | Alpaca_ TARS1 ( ortholog_one2one ) Dog_ TARS1 ( ortholog_one2one ) GuineaPig_ TARS1 ( ortholog_one2one ) Macaque_ TARS1 ( ortholog_one2one ) Mouse_ Tars ( ortholog_one2one ) Pig_ TARS1 ( ortholog_one2one ) Rat_ Tars1 ( ortholog_one2one ) Rabbit_ TARS1 ( ortholog_one2one ) |
| Ohnologs | TARS3 |
| Paralogs | TARS2, TARS3, MRPL39, PARS2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WWT (NMR - ) 4HWT (X-ray 2.30A ) 4P3N (X-ray 2.60A ) 4TTV (X-ray 2.80A ) 5XLN (X-ray 1.90A ) |
| DBSNP | rs34334786 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q9D0R2}. |
| Mouse PG classification | NA |
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