Gene Information
Gene NameCDC27
OrganismHomo sapiens (Human)
Gene Length824
Protein NamesCell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000004897 )
Evolutionary StageEuk+Bac
AlphaFoldDBP30260
Gene CardCDC27
Uniprot IDP30260
PfamPF00515; PF13181
In ASDno
Allosteric Predictionno (-0.03493394)
Ortholog in AnimalsAlpaca_ CDC27 ( ortholog_one2one )
Dog_ CDC27 ( ortholog_one2one )
GuineaPig_ CDC27 ( ortholog_one2one )
Macaque_ CDC27 ( ortholog_one2one )
Mouse_ Cdc27 ( ortholog_one2one )
Pig_ CDC27 ( ortholog_one2one )
Rat_ Cdc27 ( ortholog_one2one )
Rabbit_ CDC27 ( ortholog_one2one )
OhnologsNA
ParalogsANAPC7, CDC23, CDC16
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.16623(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3T1N  (X-ray  2.60A  )  4RG6  (X-ray  3.30A  )  4RG7  (X-ray  4.25A  )  4RG9  (X-ray  3.25A  )  4UI9  (EM  3.60A  )  5A31  (EM  4.30A  )  5G04  (EM  4.00A  )  5G05  (EM  3.40A  )  5KHR  (EM  6.10A  )  5KHU  (EM  4.80A  )  5L9T  (EM  6.40A  )  5L9U  (EM  6.40A  )  5LCW  (EM  4.00A  )  6Q6G  (EM  3.20A  )  6Q6H  (EM  3.20A  )  6TLJ  (EM  3.80A  )  6TM5  (EM  3.90A  )  6TNT  (EM  3.78A  )  7QE7  (EM  2.90A  ) 
DBSNP rs202052665 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:18445686}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18445686}.
Mouse PG classificationNA
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